[HTML][HTML] Mouse glucocorticoid receptor phosphorylation status influences multiple functions of the receptor protein
JC Webster, CM Jewell, JE Bodwell, A Munck… - Journal of Biological …, 1997 - ASBMB
Although studies have shown that the mouse glucocorticoid receptor (mGR) contains eight
phosphorylation sites (Bodwell, JE, Ortí, E., Coull, JM, Pappin, DJC, Smith, LI, and Swift,
F.(1991) J. Biol. Chem. 266, 7549-7555), the effect of phosphorylation on receptor function is
unclear. We have examined the consequences of single or multiple phosphorylation site
mutations on several properties of mGR including receptor expression, ligand-dependent
nuclear translocation, hormone-mediated transactivation, ligand-dependent down …
phosphorylation sites (Bodwell, JE, Ortí, E., Coull, JM, Pappin, DJC, Smith, LI, and Swift,
F.(1991) J. Biol. Chem. 266, 7549-7555), the effect of phosphorylation on receptor function is
unclear. We have examined the consequences of single or multiple phosphorylation site
mutations on several properties of mGR including receptor expression, ligand-dependent
nuclear translocation, hormone-mediated transactivation, ligand-dependent down …