[HTML][HTML] Human liver infiltrating γδ T cells are composed of clonally expanded circulating and tissue-resident populations
Background & Aims γδ T cells comprise a substantial proportion of tissue-associated
lymphocytes. However, our current understanding of human γδ T cells is primarily based on
peripheral blood subsets, while the immunobiology of tissue-associated subsets remains
largely unclear. Therefore, we aimed to elucidate the T cell receptor (TCR) diversity,
immunophenotype and function of γδ T cells in the human liver. Methods We characterised
the TCR repertoire, immunophenotype and function of human liver infiltrating γδ T cells, by …
lymphocytes. However, our current understanding of human γδ T cells is primarily based on
peripheral blood subsets, while the immunobiology of tissue-associated subsets remains
largely unclear. Therefore, we aimed to elucidate the T cell receptor (TCR) diversity,
immunophenotype and function of γδ T cells in the human liver. Methods We characterised
the TCR repertoire, immunophenotype and function of human liver infiltrating γδ T cells, by …