[HTML][HTML] Regulation of pituitary adenylate cyclase-activating polypeptide gene transcription by TTF-1, a homeodomain-containing transcription factor
MS Kim, MK Hur, YJ Son, JI Park, SY Chun… - Journal of Biological …, 2002 - ASBMB
Pituitary adenylate cyclase-activating polypeptide (PACAP) is an important
hypophysiotrophic factor as well as a regulator for immune, reproductive, and neural tissues.
We recently found that TTF-1, a homeodomain-containing transcription factor essential for
the development of the fetal diencephalon, is postnatally expressed in the hypothalamic
area and plays a transcription regulatory role for certain neurohormones. Based on the
similarity of synthesis sites between PACAP and TTF-1 and, moreover, on the presence of …
hypophysiotrophic factor as well as a regulator for immune, reproductive, and neural tissues.
We recently found that TTF-1, a homeodomain-containing transcription factor essential for
the development of the fetal diencephalon, is postnatally expressed in the hypothalamic
area and plays a transcription regulatory role for certain neurohormones. Based on the
similarity of synthesis sites between PACAP and TTF-1 and, moreover, on the presence of …