A diurnal rhythm in the occurrence and severity of asthma symptoms is almost universal with
disturbed sleep due to enhanced symptoms at night paralleled by a change in lung function.
The mechanisms involved are not completely understood. However, it appears to be related
to an exaggerated response to a circadian rhythm in lung function observed in healthy
individuals. The circadian nature of asthma must be considered in diagnosis and evaluating
the adequacy of therapy. Inhaled therapy with additional suppressive and anti-inflammatory …