Importance Ipilimumab and other immune therapies are effective treatment options for
patients with advanced melanoma but cause frequent immune-related toxic effects.
Autoimmune diseases are common, and the safety and efficacy of ipilimumab therapy in
patients with preexisting autoimmune disorders is not known. Objective To determine the
safety and efficacy of ipilimumab therapy in patients with advanced melanoma with
preexisting autoimmune disorders. Design, Setting, and Participants Retrospective review of …