Mucosal-associated invariant T cells are numerically and functionally deficient in patients with mycobacterial infection and reflect disease activity

YS Kwon, YN Cho, MJ Kim, HM Jin, HJ Jung, JH Kang… - Tuberculosis, 2015 - Elsevier
Mucosal-associated invariant T (MAIT) cells contribute to protection against certain
microorganism infections. The aims of this study were to examine the levels of MAIT cells in
pulmonary tuberculosis (TB) and nontuberculous mycobacteria (NTM) lung disease patients,
to evaluate the clinical relevance of MAIT cell levels, and to investigate the functions of MAIT
cells. Patients with pulmonary TB (ná= á35), NTM (ná= á29), and healthy controls (ná= á75)
were enrolled in the study. MAIT cell levels and functions were measured by flow cytometry …