Background. The greatest prevalence of asthma is in preschool children; however, the
clinical utility of asthma therapy for this age group is limited by a narrow therapeutic index,
long-term tolerability, and frequency and/or difficulty of administration. Inhaled
corticosteroids and inhaled cromolyn are the most commonly prescribed controller therapies
for young children with persistent asthma, although very young patients may have difficulty
using inhalers, and dose delivery can be variable. Moreover, reduced compliance with …