[HTML][HTML] A novel human serum lectin with collagen-and fibrinogen-like domains that functions as an opsonin
M Matsushita, Y Endo, S Taira, Y Sato, T Fujita… - Journal of Biological …, 1996 - ASBMB
Collectins are C-type animal lectins with both collagenous and carbohydrate recognition
domains and are involved in the first line host defense against pathogens. We report here a
novel Ca 2+-dependent and GlcNAc-binding lectin consisting of subunits of 35 kDa (P35)
with a collagen-like sequence. When P35 is isolated from human serum, it forms a
homopolymer by means of intermolecular disulfide bonding, as is the case with collectins.
P35 cDNA was cloned from a human liver cDNA library, and the deduced amino acid …
domains and are involved in the first line host defense against pathogens. We report here a
novel Ca 2+-dependent and GlcNAc-binding lectin consisting of subunits of 35 kDa (P35)
with a collagen-like sequence. When P35 is isolated from human serum, it forms a
homopolymer by means of intermolecular disulfide bonding, as is the case with collectins.
P35 cDNA was cloned from a human liver cDNA library, and the deduced amino acid …