During pregnancy, maternal uterine blood vessels undergo dramatic vascular remodeling.
However, until now, little was known about whether the lymphatic circulation undergoes
similar changes and whether these vessels interact with placental cells that invade maternal
tissue. Recent studies demonstrate that normally lymphatic vessels in the uterine wall are
highly compartmentalized where their presence is mostly detected in deeper layers. In
humans, this arrangement changes during pregnancy when extensive lymphangiogenesis …