[HTML][HTML] Detection of clonal T-cell-receptor (TCR) Vbeta rearrangements in explanted dilated cardiomyopathy hearts by semi-nested PCR, GeneScan, and direct …

JH Blohm, N Blohm, M Hummel, HH Müller… - Medical Science …, 2013 - ncbi.nlm.nih.gov
JH Blohm, N Blohm, M Hummel, HH Müller, M Rohde, R Hetzer, H Lehmkuhl, M Noutsias
Medical Science Monitor Basic Research, 2013ncbi.nlm.nih.gov
Detection of clonal T-cell-receptor (TCR) Vbeta rearrangements in explanted dilated
cardiomyopathy hearts by semi-nested PCR, GeneScan, and direct sequencing - PMC Back
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Abstract
Background
Viral infection and anti-cardiac immunity are involved in the pathogenesis of dilated cardiomyopathy (DCM). Immunity targeting particular antigens may evoke expansion of reactive T-cell clones.
ncbi.nlm.nih.gov