[HTML][HTML] Cellular immune responses to cytomegalovirus in renal transplant recipients
R Radha, S Jordan, D Puliyanda… - American Journal of …, 2005 - Elsevier
Control of CMV replication depends primarily on anti-CMV T lymphocyte activity. However,
the functional T-cell responses to CMV in immunosuppressed solid organ transplant
recipients are not well understood. In this study we employed cytokine flowcytometry (CFC)
using pooled CMV peptides and viral lysates to detect CMV-specific T-cell responses in 17
healthy controls, 33 stable renal transplant recipients (Tx recipients) and 6 transplant
recipients with active CMV infection (CMV (+)). We found that pooled peptides and lysates …
the functional T-cell responses to CMV in immunosuppressed solid organ transplant
recipients are not well understood. In this study we employed cytokine flowcytometry (CFC)
using pooled CMV peptides and viral lysates to detect CMV-specific T-cell responses in 17
healthy controls, 33 stable renal transplant recipients (Tx recipients) and 6 transplant
recipients with active CMV infection (CMV (+)). We found that pooled peptides and lysates …