[HTML][HTML] Analysis of energy metabolism in humans: A review of methodologies
YY Lam, E Ravussin - Molecular metabolism, 2016 - Elsevier
YY Lam, E Ravussin
Molecular metabolism, 2016•ElsevierBackground Obesity is a consequence of chronic energy imbalance. We need accurate and
precise measurements of energy intake and expenditure, as well as the related behaviors, to
fully understand how energy homeostasis is regulated in order to develop interventions and
evaluate their effectiveness to combat the global obesity epidemic. Scope of review We
provide an in-depth review of the methodologies currently used to measure energy intake
and expenditure in humans, including their principles, advantages, and limitations in the …
precise measurements of energy intake and expenditure, as well as the related behaviors, to
fully understand how energy homeostasis is regulated in order to develop interventions and
evaluate their effectiveness to combat the global obesity epidemic. Scope of review We
provide an in-depth review of the methodologies currently used to measure energy intake
and expenditure in humans, including their principles, advantages, and limitations in the …
Background
Obesity is a consequence of chronic energy imbalance. We need accurate and precise measurements of energy intake and expenditure, as well as the related behaviors, to fully understand how energy homeostasis is regulated in order to develop interventions and evaluate their effectiveness to combat the global obesity epidemic.
Scope of review
We provide an in-depth review of the methodologies currently used to measure energy intake and expenditure in humans, including their principles, advantages, and limitations in the clinical research setting. The aim is to provide researchers with a comprehensive guide to conduct obesity research of the highest possible quality.
Major conclusions
An array of methodologies is available to measure various aspects of energy metabolism and none is perfect under all circumstances. The choice of methods should be specific to particular research questions with practicality and quality of data the priorities for consideration. A combination of complementary measurements may be preferable. There is an imperative need to develop new methodologies to improve the accuracy and precision of energy intake assessments.
Elsevier