Effect of sex hormones on crystal formation in a stone-forming rat model
I Yoshioka, M Tsujihata, C Momohara, W Akanae… - Urology, 2010 - Elsevier
OBJECTIVES: To evaluate the contribution of sex hormones in urolithiasis using a stone-
forming rat model. Gender differences because of sex hormones are thought to influence the
incidence of urolithiasis. METHODS: We divided rats into 7 groups, such as intact males,
orchidectomized males, intact males subcutaneously implanted with testosterone, intact
males subcutaneously implanted with estradiol, intact females, ovariectomized females, and
intact females subcutaneously implanted with testosterone. At 10 weeks old, the rats were …
forming rat model. Gender differences because of sex hormones are thought to influence the
incidence of urolithiasis. METHODS: We divided rats into 7 groups, such as intact males,
orchidectomized males, intact males subcutaneously implanted with testosterone, intact
males subcutaneously implanted with estradiol, intact females, ovariectomized females, and
intact females subcutaneously implanted with testosterone. At 10 weeks old, the rats were …