Crystal structure of bovine annexin VI in a calcium-bound state
AJ Avila-Sakar, CE Creutz, RH Kretsinger - Biochimica et Biophysica Acta …, 1998 - Elsevier
The crystal structure of a calcium-bound form of bovine annexin VI has been determined
with X-ray diffraction data to 2.9 Å by molecular replacement. Six Ca2+ ions were found, five
in AB loops, one in a DE loop. Two loops (II-AB, which binds calcium, and V-AB, which does
not) have conformations that differ significantly from those in calcium-free, human
recombinant annexin VI. There are only small differences between the calci-and the apo-
annexin VI in the rest of the molecule. Calcium by itself does not promote a major …
with X-ray diffraction data to 2.9 Å by molecular replacement. Six Ca2+ ions were found, five
in AB loops, one in a DE loop. Two loops (II-AB, which binds calcium, and V-AB, which does
not) have conformations that differ significantly from those in calcium-free, human
recombinant annexin VI. There are only small differences between the calci-and the apo-
annexin VI in the rest of the molecule. Calcium by itself does not promote a major …