Sensitization to Ascaris lumbricoides and severity of childhood asthma in Costa Rica

GM Hunninghake, ME Soto-Quiros, L Avila… - Journal of Allergy and …, 2007 - Elsevier
BACKGROUND: Little is known about sensitization (defined as a positive IgE) to helminths
and disease severity in patients with asthma. OBJECTIVES: To examine the relationship
between sensitization (defined as a positive IgE) to Ascaris lumbricoides and measures of
asthma morbidity and severity in a Costa Rican population with low prevalence of parasitic
infection but high prevalence of parasitic exposure. METHODS: Cross-sectional study of 439
children (ages 6 to 14 years) with asthma. Linear regression and logistic regression were …