Restoration of short chain fatty acid and bile acid metabolism following fecal microbiota transplantation in patients with recurrent Clostridium difficile infection
A significant proportion of individuals develop recurrent Clostridium difficile infection (CDI)
following initial disease. Fecal microbiota transplantation (FMT), a highly effective treatment
method for recurrent CDI, has been demonstrated to induce microbiota recovery. One of the
proposed functions associated with restoration of colonization resistance against C. difficile
has been recovery of bile acid metabolism. In this study, we aimed to assess recovery of
short chain fatty acids (SCFAs) in addition to bile acids alongside microbial community …
following initial disease. Fecal microbiota transplantation (FMT), a highly effective treatment
method for recurrent CDI, has been demonstrated to induce microbiota recovery. One of the
proposed functions associated with restoration of colonization resistance against C. difficile
has been recovery of bile acid metabolism. In this study, we aimed to assess recovery of
short chain fatty acids (SCFAs) in addition to bile acids alongside microbial community …