Genetic control of macrophage responses.

R Van Furth, W Sluiter, JT Van Dissel - … of the New York Academy of …, 1986 - europepmc.org
R Van Furth, W Sluiter, JT Van Dissel
Annals of the New York Academy of Sciences, 1986europepmc.org
A short review of current concepts concerning the origin and kinetics of monocytes and
macrophages is given, and the humoral regulation of monocyte production by FIM, a factor
synthesized and secreted by macrophages, is discussed. Genetic control of the
responsiveness of monocyte precursors to FIM and that of the phagocytosis and intracellular
killing of bacteria is dealt with.
A short review of current concepts concerning the origin and kinetics of monocytes and macrophages is given, and the humoral regulation of monocyte production by FIM, a factor synthesized and secreted by macrophages, is discussed. Genetic control of the responsiveness of monocyte precursors to FIM and that of the phagocytosis and intracellular killing of bacteria is dealt with.
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