The epigenotype

CH Waddington - International journal of epidemiology, 2012 - academic.oup.com
CH Waddington
International journal of epidemiology, 2012academic.oup.com
The adult characteristics of animals, ie their phenotypes, must be studied in order to reach
conclusions about the genotypes, ie the hereditary constitutions which form the basic subject-
matter of genetics. But between genotype and phenotype lies a whole complex of
development processes, for which Dr Waddington proposes the name 'epigenotype.'He here
describes some of the general characteristics of an epigenotype, with special reference to
the fruit-fly Drosophila melanogaster.
Abstract
The adult characteristics of animals, i.e. their phenotypes, must be studied in order to reach conclusions about the genotypes, i.e. the hereditary constitutions which form the basic subject-matter of genetics. But between genotype and phenotype lies a whole complex of development processes, for which Dr Waddington proposes the name ‘epigenotype.’ He here describes some of the general characteristics of an epigenotype, with special reference to the fruit-fly Drosophila melanogaster.
Oxford University Press