[HTML][HTML] MicroRNA-Let-7a regulates the function of microglia in inflammation
KJ Cho, J Song, Y Oh, JE Lee - Molecular and Cellular Neuroscience, 2015 - Elsevier
Microglia have multiple functions in cerebrovascular and neurodegenerative diseases.
Regulation of microglial function during inflammatory stress is important for treatment of
central nervous system (CNS) diseases because microglia secrete various substances that
affect neurons and glia. MicroRNA-Let-7a (miR-Let-7a) is a tumor suppressor miRNA that
has been reported to target transcripts that encode proteins involved in apoptosis. In the
present study, we examined the essential role of miR-Let-7a in inflammatory stress by over …
Regulation of microglial function during inflammatory stress is important for treatment of
central nervous system (CNS) diseases because microglia secrete various substances that
affect neurons and glia. MicroRNA-Let-7a (miR-Let-7a) is a tumor suppressor miRNA that
has been reported to target transcripts that encode proteins involved in apoptosis. In the
present study, we examined the essential role of miR-Let-7a in inflammatory stress by over …