[HTML][HTML] Cirrhosis-associated immune dysfunction: distinctive features and clinical relevance
A Albillos, M Lario, M Álvarez-Mon - Journal of hepatology, 2014 - Elsevier
The term cirrhosis-associated immune dysfunction refers to the main syndromic
abnormalities of immune function, immunodeficiency and systemic inflammation that are
present in cirrhosis. The course of advanced cirrhosis, regardless of its aetiology, is
complicated by cirrhosis-associated immune dysfunction and this constitutes the
pathophysiological hallmark of an increased susceptibility to bacterial infection, distinctive of
the disease. Cirrhosis impairs the homeostatic role of the liver in the systemic immune …
abnormalities of immune function, immunodeficiency and systemic inflammation that are
present in cirrhosis. The course of advanced cirrhosis, regardless of its aetiology, is
complicated by cirrhosis-associated immune dysfunction and this constitutes the
pathophysiological hallmark of an increased susceptibility to bacterial infection, distinctive of
the disease. Cirrhosis impairs the homeostatic role of the liver in the systemic immune …