[PDF][PDF] Dopamine D4 receptor gene polymorphism is associated with attention deficit hyperactivity disorder
GJ LaHoste, JM Swanson, SB Wigal, C Glabe… - Mol …, 1996 - researchgate.net
Dopamlne ls belleved to play a major role ln the manlfestatlon of attention deflclt
hyperactivity dlsorder (ADHD), whlch affects 3-6% of school-age chlldren and shows
evidence of famillallty. The dopamine D4 receptor, whlch ls preferentlally dlstributed ln
cortlcal and llmbic reglons of the braln, ls currently of major lnterest because of the hlgh
degree of functionally relevant varlablllty in lts gene (DRD4), and the association of thls
gene wlth Novelty Seeklng behavlor. We examlned the variablllty ln the length of a reglon of …
hyperactivity dlsorder (ADHD), whlch affects 3-6% of school-age chlldren and shows
evidence of famillallty. The dopamine D4 receptor, whlch ls preferentlally dlstributed ln
cortlcal and llmbic reglons of the braln, ls currently of major lnterest because of the hlgh
degree of functionally relevant varlablllty in lts gene (DRD4), and the association of thls
gene wlth Novelty Seeklng behavlor. We examlned the variablllty ln the length of a reglon of …