[PDF][PDF] Organelles: the emerging signalling chart of mitochondrial dynamics

T Calì, G Szabadkai - Current Biology, 2018 - cell.com
Current Biology, 2018cell.com
Many molecular and functional details of single events in mitochondrial dynamics have been
reported, but little is known about their coordination. A recent study describes how cellular
Ca 2+ signals, via remodelling the actin cytoskeleton, synchronise the formation of
endoplasmic reticulum–mitochondria contacts with inner and outer mitochondrial membrane
fission.
Summary
Many molecular and functional details of single events in mitochondrial dynamics have been reported, but little is known about their coordination. A recent study describes how cellular Ca2+ signals, via remodelling the actin cytoskeleton, synchronise the formation of endoplasmic reticulum–mitochondria contacts with inner and outer mitochondrial membrane fission.
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