Reversibility of renal impairment in patients with multiple myeloma treated with bortezomib-based regimens: identification of predictive factors
Purpose Renal impairment is a frequent complication of multiple myeloma (MM) and is
associated with significant morbidity and increased early death rate. Bortezomib is active
and well tolerated in patients with MM who present or develop renal impairment. Patients
and Methods We analyzed 46 consecutive patients who presented with renal impairment in
order to evaluate the impact of bortezomib on the improvement of renal function and to
identify predictive factors associated with renal response. All patients received bortezomib …
associated with significant morbidity and increased early death rate. Bortezomib is active
and well tolerated in patients with MM who present or develop renal impairment. Patients
and Methods We analyzed 46 consecutive patients who presented with renal impairment in
order to evaluate the impact of bortezomib on the improvement of renal function and to
identify predictive factors associated with renal response. All patients received bortezomib …