[HTML][HTML] Haematopoietic cell transplantation as immunotherapy

FR Appelbaum - Nature, 2001 - nature.com
Nature, 2001nature.com
The graft-versus-tumour effect seen after allogeneic (genetically different) haematopoietic
cell transplantation for human malignancies represents the clearest example of the power of
the human immune system to eradicate cancer. Recent advances in our understanding of
the immunobiology of stem-cell engraftment, tolerance and tumour eradication are allowing
clinicians to better harness this powerful effect.
Abstract
The graft-versus-tumour effect seen after allogeneic (genetically different) haematopoietic cell transplantation for human malignancies represents the clearest example of the power of the human immune system to eradicate cancer. Recent advances in our understanding of the immunobiology of stem-cell engraftment, tolerance and tumour eradication are allowing clinicians to better harness this powerful effect.
nature.com