[PDF][PDF] The biological activities of groß and IL-8 on human neutrophils are overlapping but not identical
M Magazin, N Vita, E Cavrois, S Lefort… - Eur. Cytokine …, 1992 - researchgate.net
Groß and IL-8 are two members of the small induced secreted (SIS) cytokine family (CXC
subgroup) with proinflammatory activities on neutrophils. In order to assess whether or not
the interaction with their receptors results in similar" biological actions, we compared the two
cytokines in five different bioassays. Groß showed similar biological activities as IL-8 in tests
of chemotaxis, induction of the respiratory burst, and induction of interleukin 6 (IL-6)
production. However, for two other biological activities: augmentation of the expression of …
subgroup) with proinflammatory activities on neutrophils. In order to assess whether or not
the interaction with their receptors results in similar" biological actions, we compared the two
cytokines in five different bioassays. Groß showed similar biological activities as IL-8 in tests
of chemotaxis, induction of the respiratory burst, and induction of interleukin 6 (IL-6)
production. However, for two other biological activities: augmentation of the expression of …