Concentration and distribution of polysaccharides in human cortical bone and the dentine of teeth
HJ Rogers - Nature, 1949 - nature.com
HJ Rogers
Nature, 1949•nature.comTHE probable presence of a sulphated polysaccharide in bone has been recognized for
many years1. Recently, attention has been redirected to the subject by the isolation2 of a
substance claimed to be identical with chondrontin sulphate, which is known to be one of the
principal constituents of cartilage1, 3, from dentine of human teeth. As a basis for future work
on the organic matrix of bone and teeth it seems to be of importance to know:(1) the order of
concentration of the mucopolysaccharides in them;(2) the changes, if any, which take place …
many years1. Recently, attention has been redirected to the subject by the isolation2 of a
substance claimed to be identical with chondrontin sulphate, which is known to be one of the
principal constituents of cartilage1, 3, from dentine of human teeth. As a basis for future work
on the organic matrix of bone and teeth it seems to be of importance to know:(1) the order of
concentration of the mucopolysaccharides in them;(2) the changes, if any, which take place …
Abstract
THE probable presence of a sulphated polysaccharide in bone has been recognized for many years1. Recently, attention has been redirected to the subject by the isolation2 of a substance claimed to be identical with chondrontin sulphate, which is known to be one of the principal constituents of cartilage1,3, from dentine of human teeth. As a basis for future work on the organic matrix of bone and teeth it seems to be of importance to know: (1) the order of concentration of the mucopolysaccharides in them ; (2) the changes, if any, which take place with age ; (3) the distribution of polysaccharide. The present work is a contribution to problems (1) and (3). Insufficient samples have yet been analysed to give an answer to point (2), but the following is a preliminary summary of the results so far obtained.
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