Periosteal bone formation—a neglected determinant of bone strength
E Seeman - New England Journal of Medicine, 2003 - Mass Medical Soc
E Seeman
New England Journal of Medicine, 2003•Mass Medical SocLife forms that have low body mass can hunt for food on the undersurface of branches or
along shear cliff faces quite unperturbed by gravity. For larger animals, the hunt for dinner
and the struggle to avoid becoming someone else's meal require rapid movement against
gravity. This need is met by the lever function of long bones, three-dimensional
masterpieces of biomechanical engineering that, by their material composition and structural
design, achieve the contradictory properties of stiffness and flexibility, strength and lightness …
along shear cliff faces quite unperturbed by gravity. For larger animals, the hunt for dinner
and the struggle to avoid becoming someone else's meal require rapid movement against
gravity. This need is met by the lever function of long bones, three-dimensional
masterpieces of biomechanical engineering that, by their material composition and structural
design, achieve the contradictory properties of stiffness and flexibility, strength and lightness …
Life forms that have low body mass can hunt for food on the undersurface of branches or along shear cliff faces quite unperturbed by gravity. For larger animals, the hunt for dinner and the struggle to avoid becoming someone else's meal require rapid movement against gravity. This need is met by the lever function of long bones, three-dimensional masterpieces of biomechanical engineering that, by their material composition and structural design, achieve the contradictory properties of stiffness and flexibility, strength and lightness.1
Material stiffness results from the encrusting of the triple-helical structure of collagen type I with hydroxyapatite crystals, which confers . . .
The New England Journal Of Medicine