Mouse Endogenous Superantigens: Ms and Mls‐like Determinants Encoded by Mouse Retroviruses

RJ Hodes, R Abe - Current protocols in immunology, 1996 - Wiley Online Library
Commonly used inbred mouse strains express different combinations of integrated mouse
mammary tumor proviruses (MMTV). This appendix summarizes the proviruses that have
been detected. The reported functional properties of those MMTV proviral products which
have been identified as superantigens are also summarized, including the ability to elicit
primary or secondary T cell responses and to induce Vb‐specific clonal deletion during T
cell differentiation. In addition, the amino acid sequences of putative ORF gene products of …