In mammalian evolution, three types of adipocytes have developed, white, brown and beige
adipocytes. White adipocytes are the major constituents of white adipose tissue (WAT), the
predominant store for energy-dense triglycerides in the body that are released as fatty acids
during catabolic conditions. The less abundant brown adipocytes, the defining parenchymal
cells of brown adipose tissue (BAT), internalize triglycerides that are stored intracellularly in
multilocular lipid droplets. Beige adipocytes (also known as brite or inducible brown …