Significant relationship of matrix metalloproteinase 9 with nuclear grade and prognostic impact of tissue inhibitor of metalloproteinase 2 for incidental clear cell renal …

N Kawata, Y Nagane, H Hirakata, T Ichinose, Y Okada… - Urology, 2007 - Elsevier
OBJECTIVE: To examine the immunoreactivity of tumors for matrix metalloproteinases 2 and
9 (MMP-2, MMP-9), tissue inhibitors of metalloproteinases 1 and 2 (TIMP-1, TIMP-2), and
membrane type MMP 1 (MT-MMP-1), to evaluate the optimum assessment of incidental
renal cell carcinoma. METHODS: Tumor samples from 120 incidental clear cell renal cell
carcinoma (ICRCC) patients without distant metastasis or invasion beyond Gerota's fascia
were obtained by surgery. They were immunohistochemically stained for MMP-2, MMP-9 …