Of Wnts and ribosomes

AS Pfister, M Kühl - Progress in molecular biology and translational …, 2018 - Elsevier
Wnt proteins are secreted glycoproteins that activate different intracellular signal
transduction pathways. They regulate cell proliferation and are required for proper
embryonic development. Misregulation of Wnt signaling can result in various diseases
including cancer. In most circumstances, cell growth is essential for cell division and thus
cell proliferation. Therefore, several reports have highlighted the key role of Wnt proteins for
cell growth. Ribosomes represent the cellular protein synthesis machinery and cells need to …