Predictive value of HLA-G and HLA-E in the prognosis of colorectal cancer patients

ZY Guo, YG Lv, L Wang, SJ Shi, F Yang, GX Zheng… - Cellular …, 2015 - Elsevier
Abstract HLA-G and HLA-E are non-classical HLA Ib molecules. Recently, increasingly more
reports have shown that HLA-G is highly expressed in different malignancies. In this article,
we detected the expression levels of HLA-G and HLA-E in primary colorectal cancer
patients. Our results showed that 70.6% and 65.7% of the colorectal cancer tissues had
positive HLA-G or HLA-E expression, respectively, and that 46.1% positively expressed both
molecules. We also analyzed the correlations between the expression levels of HLA-G, HLA …