Androgen pretreatment in poor responders undergoing controlled ovarian stimulation and in vitro fertilization treatment

SK Sunkara, A Coomarasamy - Fertility and sterility, 2011 - fertstert.org
We updated our meta-analysis (1) after the recent publication of a randomized controlled
trial (RCT) evaluating the effect of T pretreatment in poor responders undergoing IVF
treatment (2). Our updated meta-analysis of RCTs of adjuvant androgens (DHEA and T) in
poor responders showed a significant improvement in the ongoing pregnancy/live-birth rates
(relative risk, 2.08; 95% confidence interval [CI],[1.10, 3.93]; P¼. 002; Fig. 1). Metaanalysis
for the outcome of total dose of gonadotropin consumption showed a significantly lower …