The family of IL-10-related cytokines and their receptors: related, but to what extent?
SV Kotenko - Cytokine & growth factor reviews, 2002 - Elsevier
Five novel cytokines (IL-19, IL-20, IL-22 (IL-TIF), IL-24 (human MDA-7, mouse FISP, rat
C49A/Mob-5), and IL-26 (AK155)) demonstrating limited primary sequence identity and
probable structural homology to IL-10 have been identified. These cellular cytokines, as well
as several cytokines encoded in viral genomes (viral cytokines), form a family of IL-10-
related cytokines or the IL-10 family. These cytokines share not only homology but also
receptor subunits and perhaps activities. Receptors for these cytokines belong to the class II …
C49A/Mob-5), and IL-26 (AK155)) demonstrating limited primary sequence identity and
probable structural homology to IL-10 have been identified. These cellular cytokines, as well
as several cytokines encoded in viral genomes (viral cytokines), form a family of IL-10-
related cytokines or the IL-10 family. These cytokines share not only homology but also
receptor subunits and perhaps activities. Receptors for these cytokines belong to the class II …