TSLP expression induced via Toll-like receptor pathways in human keratinocytes
T Takai, X Chen, Y Xie, AT Vu, TA Le, H Kinoshita… - Methods in …, 2014 - Elsevier
The skin epidermis and mucosal epithelia (airway, ocular tissues, gut, and so on) are
located at the interface between the body and environment and have critical roles in the
response to various stimuli. Thymic stromal lymphopoietin (TSLP), a cytokine expressed
mainly by epidermal keratinocytes (KCs) and mucosal epithelial cells, is a critical factor
linking the innate response at barrier surfaces to Th2-skewed acquired immune response.
TSLP is highly expressed in skin lesions of atopic dermatitis patients. Here, we describe on …
located at the interface between the body and environment and have critical roles in the
response to various stimuli. Thymic stromal lymphopoietin (TSLP), a cytokine expressed
mainly by epidermal keratinocytes (KCs) and mucosal epithelial cells, is a critical factor
linking the innate response at barrier surfaces to Th2-skewed acquired immune response.
TSLP is highly expressed in skin lesions of atopic dermatitis patients. Here, we describe on …