A combination of dexamethasone and anti–IL-17A treatment can alleviate diesel exhaust particle–induced steroid insensitive asthma

EB Brandt, GKK Hershey - Journal of Allergy and Clinical Immunology, 2016 - jacionline.org
924 LETTERS TO THE EDITOR of patients with severe asthma with high DEP exposure may
be beneficial alone or in combination with steroids. A significant proportion of patients with
asthma remain symptomatic despite treatment with high-dose inhaled corticosteroids. This
group has been defined as having severe asthma, refractory asthma, or treatment-resistant
asthma. This group of patients comprises about 15% of patients with asthma but accounts for
more than 50% of health care utilization related to this disease. 7 Although it is evident that …