The biology of thymic stromal lymphopoietin (TSLP)
SF Ziegler, F Roan, BD Bell, TA Stoklasek… - Advances in …, 2013 - Elsevier
Originally shown to promote the growth and activation of B cells, thymic stromal
lymphopoietin (TSLP) is now known to have wide-ranging impacts on both hematopoietic
and nonhematopoietic cell lineages, including dendritic cells, basophils, eosinophils, mast
cells, CD4+, CD8+ and natural killer T cells, B cells and epithelial cells. While TSLP's role in
the promotion of TH2 responses has been extensively studied in the context of lung-and skin-
specific allergic disorders, it is becoming increasingly clear that TSLP may impact multiple …
lymphopoietin (TSLP) is now known to have wide-ranging impacts on both hematopoietic
and nonhematopoietic cell lineages, including dendritic cells, basophils, eosinophils, mast
cells, CD4+, CD8+ and natural killer T cells, B cells and epithelial cells. While TSLP's role in
the promotion of TH2 responses has been extensively studied in the context of lung-and skin-
specific allergic disorders, it is becoming increasingly clear that TSLP may impact multiple …