IL-9 expression by human eosinophils: regulation by IL-1β and TNF-α
AS Gounni, E Nutku, L Koussih, F Aris… - Journal of allergy and …, 2000 - Elsevier
Background: IL-9 is a pleiotropic cytokine that exhibits biologic activity on cells of diverse
hemopoietic lineage. IL-9 stimulates the proliferation of activated T cells, enhances the
production of IgE from B cells, and promotes the proliferation and differentiation of mast cells
and hematopoietic progenitors. Objective: In this study we evaluated the expression of IL-9
messenger (m) RNA and protein by human peripheral blood eosinophils. We also
investigated the role of IL-1β and TNF-α in the release of IL-9 from human peripheral blood …
hemopoietic lineage. IL-9 stimulates the proliferation of activated T cells, enhances the
production of IgE from B cells, and promotes the proliferation and differentiation of mast cells
and hematopoietic progenitors. Objective: In this study we evaluated the expression of IL-9
messenger (m) RNA and protein by human peripheral blood eosinophils. We also
investigated the role of IL-1β and TNF-α in the release of IL-9 from human peripheral blood …