Detection of pathogenic bacteria during rhinovirus infection is associated with increased respiratory symptoms and asthma exacerbations

KM Kloepfer, WM Lee, TE Pappas, TJ Kang… - Journal of allergy and …, 2014 - Elsevier
Background Detection of either viral or bacterial pathogens is associated with wheezing in
children; however, the influence of both bacteria and viruses on illness symptoms has not
been described. Objective We evaluated bacterial detection during the peak rhinovirus
season in children with and without asthma to determine whether an association exists
between bacterial infection and the severity of rhinovirus-induced illnesses. Methods Three
hundred eight children (166 with asthma and 142 without asthma) aged 4 to 12 years …