A randomized controlled study of peanut oral immunotherapy: clinical desensitization and modulation of the allergic response
P Varshney, SM Jones, AM Scurlock, TT Perry… - Journal of Allergy and …, 2011 - Elsevier
BACKGROUND: Open-label oral immunotherapy (OIT) protocols have been used to treat
small numbers of patients with peanut allergy. Peanut OIT has not been evaluated in double-
blind, placebo-controlled trials. OBJECTIVE: To investigate the safety and effectiveness of
OIT for peanut allergy in a double-blind, placebo-controlled study. METHODS: In this
multicenter study, children ages 1 to 16 years with peanut allergy received OIT with peanut
flour or placebo. Initial escalation, build-up, and maintenance phases were followed by an …
small numbers of patients with peanut allergy. Peanut OIT has not been evaluated in double-
blind, placebo-controlled trials. OBJECTIVE: To investigate the safety and effectiveness of
OIT for peanut allergy in a double-blind, placebo-controlled study. METHODS: In this
multicenter study, children ages 1 to 16 years with peanut allergy received OIT with peanut
flour or placebo. Initial escalation, build-up, and maintenance phases were followed by an …