Clinical efficacy and immune regulation with peanut oral immunotherapy
SM Jones, L Pons, JL Roberts, AM Scurlock… - Journal of Allergy and …, 2009 - Elsevier
BACKGROUND: Oral immunotherapy (OIT) has been thought to induce clinical
desensitization to allergenic foods, but trials coupling the clinical response and immunologic
effects of peanut OIT have not been reported. OBJECTIVE: The study objective was to
investigate the clinical efficacy and immunologic changes associated with OIT. METHODS:
Children with peanut allergy underwent an OIT protocol including initial day escalation,
buildup, and maintenance phases, and then oral food challenge. Clinical response and …
desensitization to allergenic foods, but trials coupling the clinical response and immunologic
effects of peanut OIT have not been reported. OBJECTIVE: The study objective was to
investigate the clinical efficacy and immunologic changes associated with OIT. METHODS:
Children with peanut allergy underwent an OIT protocol including initial day escalation,
buildup, and maintenance phases, and then oral food challenge. Clinical response and …