High expression of integrin β1 and p53 is a greater poor prognostic factor than clinical stage in small-cell lung cancer
F Oshita, Y Kameda, N Hamanaka… - American journal of …, 2004 - journals.lww.com
The purpose of this study was to investigate the possible association between expression of
integrin β1 and p53 and survival in patients with small-cell lung cancer (SCLC). One
hundred four patients with SCLC who had received an initial course of a full-dose of
combination chemotherapy between February 1989 and July 1999 were entered in the
study. Transbronchial biopsy specimens of tumors obtained before chemotherapy were
subjected to immunostaining for integrin β1 and p53. Twenty-eight and 58 patients could not …
integrin β1 and p53 and survival in patients with small-cell lung cancer (SCLC). One
hundred four patients with SCLC who had received an initial course of a full-dose of
combination chemotherapy between February 1989 and July 1999 were entered in the
study. Transbronchial biopsy specimens of tumors obtained before chemotherapy were
subjected to immunostaining for integrin β1 and p53. Twenty-eight and 58 patients could not …