[HTML][HTML] Cytoskeletal changes in hypoxic pulmonary endothelial cells are dependent on MAPK-activated protein kinase MK2
US Kayyali, CM Pennella, C Trujillo, O Villa… - Journal of Biological …, 2002 - ASBMB
Exposure to hypoxia causes structural changes in the endothelial cell layer that alter its
permeability and its interaction with leukocytes and platelets. One of the well characterized
cytoskeletal changes in response to stress involves the reorganization of the actin
cytoskeleton and the formation of stress fibers. This report describes cytoskeletal changes in
pulmonary microvascular endothelial cells in response to hypoxia and potential
mechanisms involved in this process. The hypoxia-induced actin redistribution appears to …
permeability and its interaction with leukocytes and platelets. One of the well characterized
cytoskeletal changes in response to stress involves the reorganization of the actin
cytoskeleton and the formation of stress fibers. This report describes cytoskeletal changes in
pulmonary microvascular endothelial cells in response to hypoxia and potential
mechanisms involved in this process. The hypoxia-induced actin redistribution appears to …