Effects of anisomycin on LTP in the hippocampal CA1: long-term analysis using optical recording
H Mochida, K Sato, S Sasaki, I Yazawa, K Kamino… - …, 2001 - journals.lww.com
Long-term potentiation (LTP) in the hippocampal CA1 region and in the dentate gyrus
consists of different stages: early LTP lasting minutes or several hours, and late LTP lasting
longer than 4 h. It has been suggested that the late phase of LTP is dependent on protein
synthesis. However, the experimental results of the effects of protein synthesis inhibitors are
still confusing. We applied optical recording techniques to rat hippocampal slices, and re-
evaluated the effects of a protein synthesis inhibitor, anisomycin, on LTP. Using a voltage …
consists of different stages: early LTP lasting minutes or several hours, and late LTP lasting
longer than 4 h. It has been suggested that the late phase of LTP is dependent on protein
synthesis. However, the experimental results of the effects of protein synthesis inhibitors are
still confusing. We applied optical recording techniques to rat hippocampal slices, and re-
evaluated the effects of a protein synthesis inhibitor, anisomycin, on LTP. Using a voltage …