[PDF][PDF] Regulation of V-ATPase activity

C McGuire, L Stransky, K Cotter… - Front Biosci (Landmark …, 2017 - article.imrpress.com
C McGuire, L Stransky, K Cotter, M Forgac
Front Biosci (Landmark Ed), 2017article.imrpress.com
609 1. ABSTRACT 2. INTRODUCTION Regulation of V-ATPase activity Christina McGuire1,
Laura Stransky2, Kristina Cotter2, Michael F Page 1 609 [Frontiers in Bioscience, Landmark,
22, 609-622, January 1, 2017] 1. ABSTRACT V-ATPases are ATP-driven proton pumps present
in both intracellular and cell surface membranes of eukaryotes that function in many normal and
disease processes. V-ATPases are large, multi-subunit complexes composed of a peripheral
domain (V 1 ) that hydrolyzes ATP and a membrane integral domain (V 0 ) that translocates …
Abstract
V-ATPases are ATP-driven proton pumps present in both intracellular and cell surface membranes of eukaryotes that function in many normal and disease processes. V-ATPases are large, multi-subunit complexes composed of a peripheral domain (V
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