Hereditary angioneurotic edema: II. Deficiency of inhibitor for serum globulin permeability factor and/or plasma kallikrein
NS Landerman, ME Webster, EL Becker, HE Ratcliffe - Journal of Allergy, 1962 - Elsevier
Studies of a 33-year-old Caucasian woman with hereditary angioneurotic edema and her
two sons, of whom only one is definitely affected with the disease, have revealed that the
inborn biochemical lesion is likely an inherited deficiency of serum inhibitor to plasma
kallikrein and/or serum globulin permeability factor. The patient showed a significantly
greater bluing response to intradermal injections of diluted autologous serum or to plasma
kallikrein than did the normal controls and this response, unlike that of the control subjects …
two sons, of whom only one is definitely affected with the disease, have revealed that the
inborn biochemical lesion is likely an inherited deficiency of serum inhibitor to plasma
kallikrein and/or serum globulin permeability factor. The patient showed a significantly
greater bluing response to intradermal injections of diluted autologous serum or to plasma
kallikrein than did the normal controls and this response, unlike that of the control subjects …