Taming tissue-specific T cells: CTLA-4 reins in self-reactive T cells
AM Paterson, AH Sharpe - Nature immunology, 2010 - nature.com
AM Paterson, AH Sharpe
Nature immunology, 2010•nature.comTaming tissue-specific T cells: CTLA-4 reins in self-reactive T cells | Nature Immunology Skip to
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CTLA-4 is a potent coinhibitory molecule that is critical for peripheral T cell tolerance. New data suggest that CTLA-4 exerts its critical immunoregulatory functions by controlling antigen-specific conventional T cells as well as regulatory T cells.
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