Recipient-derived hepatocytes in liver transplants: a rare event in sex-mismatched transplants

F Fogt, KH Beyser, C Poremba, RL Zimmerman… - Hepatology, 2002 - journals.lww.com
Bone marrow-derived stem cells have been shown to engraft and populate native tissues
during repair and in transplanted animal tissues. Very few studies have been performed in
humans to evaluate the possibility of stem cell engraftment in transplanted tissues. In human
renal transplants, recipient cells have been demonstrated within vascular and interstitial
structures. In a previous study of patients with hepatic transplants, hepatocytes with XY
chromosome patterns have been detected in sex-mismatched female to male transplanted …