[HTML][HTML] The minor allele of GP6 T13254C is associated with decreased platelet activation and a reduced risk of recurrent cardiovascular events and mortality: results …
JD Snoep, P Gaussem, JCJ Eikenboom… - Journal of thrombosis …, 2010 - Elsevier
Background: Contradictory results have been published on the effects of T13254C
(rs1613662), which distinguishes the two major isoforms of GP6, the gene encoding the
platelet receptor glycoprotein VI, on platelet function and the risk of cardiovascular disease.
Methods: We performed a population‐based case–control study, the Study of Myocardial
Infarctions in Leiden, among 547 male patients with a first myocardial infarction (MI) and 646
control subjects, as well as a prospective cohort study in which the same MI patients were …
(rs1613662), which distinguishes the two major isoforms of GP6, the gene encoding the
platelet receptor glycoprotein VI, on platelet function and the risk of cardiovascular disease.
Methods: We performed a population‐based case–control study, the Study of Myocardial
Infarctions in Leiden, among 547 male patients with a first myocardial infarction (MI) and 646
control subjects, as well as a prospective cohort study in which the same MI patients were …