In this chapter we review the association between SLE and C1q. In the first part of the
chapter we discuss the clinical associations of C1q deficiency, and tabulate the available
information in the literature relating to C1q deficiency and autoimmune disease. Other
clinical associations of C1q deficiency are then considered, and we mention briefly the
association between other genetically determined complement deficiencies and lupus. In
the review we explore the relationship between C1q consumption and lupus and we discuss …